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Patients treated with REMICADE are at increased risk for developing serious infections that may lead to hospitalization or death [see WARNINGS AND PRECAUTIONS and ADVERSE REACTIONS]. Most patients who developed these infections were taking concomitant immunosuppressants such as methotrexate or corticosteroids. REMICADE should be discontinued if a patient develops a serious infection or sepsis. Reported infections include:The flexible container is fabricated from a specially formulated non-plasticized, thermoplastic copolyester (CR3). The amount of water that can permeate from the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the flexible container can leach out certain of the container's chemical components in very small amounts within the expiration period. The suitability of the container material has been confirmed by tests in animals according to USP biological tests for plastic containers.

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Frequency not reported: QT interval prolongation, torsades de pointes, tachycardia, thrombophlebitisVigabatrin is under a restricted-use program primarily because it can cause vision loss in anyone who takes it, at any dose. Visual loss commonly includes loss of peripheral vision. Vigabatrin has also been linked to suicidal thoughts.Sustiva must not be used in patients with severe liver disease or who are taking any of the following medicines:

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Uncommon (0.1% to 1%): Pancreatitis, flatulence

Hypoglycemia, or low blood sugar, is the most common side effect of insulin glargine. Symptoms include headache, hunger, weakness, sweating, tremors, irritability, trouble concentrating, rapid breathing, fast heartbeat, fainting, or seizure (severe hypoglycemia can be fatal). Carry hard candy or glucose tablets...

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